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VIP Receptor 1 Antagonist / [Ac-His1, D-Phe2, Lys15, Arg16, Leu27]-VIP (1-7) - GRF (8-27)

Quantity:

Catalog #
Size
Price
064-25 200 µg $167

Sequence:  ()
Ac-His-D-Ph)-Asp-Ala-Val-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Lys-Arg-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-NH2
  • Molecular Weight:
  • 3273.9
  • Purity:
  • ≥ 95%
  • Validation:
  • Exhibits correct molecular weight
  • Solubility:
  • Soluble in water
  • Storage:
  • Up to 6 months in lyophilized form at 0-5°C.
    For best results, rehydrate just before use.
    After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
  • Appearance:
  • White powder
  • Contents:
  • Each vial contains 200 µg of NET peptide.

Glucagon-like peptide-1 modulates neurally evoked mucosal chloride secretion in guinea pig small intestine in vitro.
Baldassano S, Wang GD, Mulè F, Wood JD. Am J Physiol Gastrointest Liver Physiol. 2012;302(3):G352-8.

A systematic comparison of intracellular cyclic AMP and calcium signalling highlights complexities in human VPAC/PAC receptor pharmacology.
Dickson L, Aramori I, Mcculloch J, Sharkey J, Finlayson K. Neuropharmacology. 2006;51(6):1086-98.

Neurogenic secretion mediated by the purinergic P2Y1 receptor in guinea-pig small intestine.
Fang X, Hu HZ, Gao N, et al. Eur J Pharmacol. 2006;536(1-2):113-22.

Cutting edge: vasoactive intestinal peptide acts as a potent suppressor of inflammation in vivo by trans-deactivating chemokine receptors.
Grimm MC, Newman R, Hassim Z, et al. J Immunol. 2003;171(10):4990-4.

In vitro properties of a high affinity selective antagonist of the VIP1 receptor.
Gourlet P, De neef P, Cnudde J, Waelbroeck M, Robberecht P. Peptides. 1997;18(10):1555-60.

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