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Neurotensin (Human, Rat, Mouse) - EIA Kit

Quantity:

Catalog #
Size
Price
EK-048-03 96 wells $570

  • Protocol:
  • View/Download (PDF) - for reference only
  • Sample Preparation:
  • Suggested Procedure
  • Measured Sample Levels: polaroid
    Measured values represent approximate 'normal' levels in sample, but do not signify the only possible sample levels. Various factors (e.g. sample storage, assay procedure) can affect results.
  • Human Plasma: 0.59 ng/ml
    Rat Plasma: 0.78 ng/ml
    Rat Serum: 0.56 ng/ml
    Mouse Plasma: 0.71 ng/ml
    Mouse Serum: 0.59 ng/ml
  • Sample Extraction:
  • Recommended
  • Sensitivity: polaroid
    Data may differ slightly based on lot.
  • 0.2 ng/ml
  • Linear Range: polaroid
    Data may differ slightly based on lot.
  • 0.2 - 3.51 ng/ml
  • Cross Reactivity:
  • Peptide %
    Neurotensin (Human, Rat, Mouse) 100
    Neurotensin (Guinea Pig) 26
    Neuromedin N (Porcine) 0.03
    Substance P 0
    Kinetensin 0
    Bombesin 0

  • Intra-assay variation:
  • <10%
  • Inter-assay variation:
  • <15%
Standard Curve:

The effect of curcumin on oxaliplatin and cisplatin neurotoxicity in rats: some behavioral, biochemical, and histopathological studies.
Al moundhri MS, Al-salam S, Al mahrouqee A, Beegam S, Ali BH. J Med Toxicol. 2013;9(1):25-33.

PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport.
Li J, Song J, Cassidy MG, et al. Mol Endocrinol. 2012;26(8):1380-93.

Androgen-independent growth and tumorigenesis of prostate cancer cells are enhanced by the presence of PKA-differentiated neuroendocrine cells.
Deeble PD, Cox ME, Frierson HF, et al. Cancer Res. 2007;67(8):3663-72.

Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated rats.
Jalkanen AJ, Puttonen KA, Venäläinen JI, et al. Basic Clin Pharmacol Toxicol. 2007;100(2):132-8.

Cyclic adenosine 5'-monophosphate-stimulated neurotensin secretion is mediated through Rap1 downstream of both Epac and protein kinase A signaling pathways.
Li J, O'connor KL, Cheng X, et al. Mol Endocrinol. 2007;21(1):159-71.

Impact and mechanisms of action of neurotensin on cardiac contractility in the rat left ventricle.
Osadchii O, Norton G, Deftereos D, Badenhorst D, Woodiwiss A. Eur J Pharmacol. 2005;520(1-3):108-17.

Inhibition of mitochondrial gene transcription suppresses neurotensin secretion in the human carcinoid cell line BON.
Li N, Wang Q, Li J, et al. Am J Physiol Gastrointest Liver Physiol. 2005;288(2):G213-20.

A high-yield method to extract peptides from rat brain tissue.
Kline TR, Pang J, Hefta SA, Opiteck GJ, Kiefer SE, Scheffler JE. Anal Biochem. 2003;315(2):183-8.