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BNP-32 (Canine)

Quantity:

Catalog #
Size
Price
011-22 200 µg $167

Sequence:  ()
Ser-Pro-Lys-Met-Met-His-Lys-Ser-Gly-Cys-Phe-Gly-Arg-Arg-Leu-Asp-Arg-Ile-Gly-Ser-Leu-Ser-Gly-Leu-Gly-Cys-Asn-Val-Leu-Arg-Lys-Tyr
Disulfide bridge(s): Cys10-Cys26
  • Molecular Weight:
  • 3566.29
  • Purity:
  • ≥ 95%
  • Validation:
  • Exhibits correct molecular weight
  • Solubility:
  • Soluble in water
  • Storage:
  • Up to 6 months in lyophilized form at 0-5°C.
    For best results, rehydrate just before use.
    After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
  • Appearance:
  • White powder
  • Contents:
  • Each vial contains 200 µg of NET peptide.

Analytical validation of commercial immunoassays for the measurement of cardiovascular peptides in the dog.
Schellenberg S, Grenacher B, Kaufmann K, Reusch CE, Glaus TM. Vet J. 2008;178(1):85-90.

Acute phosphodiesterase 5 inhibition mimics hemodynamic effects of B-type natriuretic peptide and potentiates B-type natriuretic peptide effects in failing but not normal canine heart.
Forfia PR, Lee M, Tunin RS, Mahmud M, Champion HC, Kass DA. J Am Coll Cardiol. 2007;49(10):1079-88.

Maximizing the renal cyclic 3'-5'-guanosine monophosphate system with type V phosphodiesterase inhibition and exogenous natriuretic peptide: a novel strategy to improve renal function in experimental overt heart failure.
Chen HH, Huntley BK, Schirger JA, Cataliotti A, Burnett JC. J Am Soc Nephrol. 2006;17(10):2742-7.

Brain natriuretic Peptide is produced in cardiac fibroblasts and induces matrix metalloproteinases.
Tsuruda T, Boerrigter G, Huntley BK, et al. Circ Res. 2002;91(12):1127-34.

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